Which meds are used to rapidly induce unconsciousness and facilitate instrumentation of the airway via IV induction?

• A. Propofol
• B. Lidocaine
• C. Fentanyl
• D. Rocuronium

Answer: (A)

Induction for airway instrumentation relies on a hypnotic that can rapidly produce loss of consciousness. Propofol fits this role best because its onset is very rapid (often within about 30 seconds) and its duration is short, allowing quick, smooth induction and swift ability to control the airway. Fentanyl provides analgesia and can blunt hemodynamic responses but doesn’t reliably cause unconsciousness by itself. Lidocaine can blunt coughing or reflexes during airway manipulation but does not induce hypnosis. Rocuronium is a neuromuscular blocker that facilitates intubation by paralysis but does not produce sedation or loss of consciousness. So, propofol is the correct choice for rapid IV induction and facilitating airway instrumentation.